Aaron Leconte

Aaron Leconte, Ph.D

Associate Professor of Chemistry

Keck Science
Areas of Expertise:
Biochemistry, Biotechnology

Aaron Leconte
Keck Science Center 214


CHEM14L: Basic Principles of Chemistry (Lab only; F12, F13)
CHEM29L: Accelerated General Chemistry (Lecture only; F14)
CHEM40L: Introduction to Biological Chemistry (F15, F16, F17)
CHEM127L: Advanced Laboratory II (S13, S14, S15, S17)
BIO/CHEM177: Biochemistry (F12, F13, F14, S15, S18)
CHEM180: Applied Biomolecular Evolution (S14, S18)

  • Education
  • Research and Publications
B.A., Chemistry, Carleton College (2000-2004); Ph.D., Chemical Biology, The Scripps Research Institute (2004-2009); NIH Postdoctoral Fellow, Harvard University (2009-2012).
  • E. L. Lewis and A. M. Leconte. (in press). DNA polymerase activity assay using near-infrared fluorscent labeled DNA visualized by acrylamide gel electrophoresis. Journal of Visualized Experiments

  • S. L. Rosenblum, A. G. Weiden, E. L. Lewis, A. L. Ogonowsky, H. E. Chia, S. E. Barrett, M. D. Liu, and A. M. Leconte . (2017). Design and discovery of new combinations of mutant DNA polymerases and modified DNA substrates. Chembiochem 18: 816.

  • H.J. Schultz, A. M. Gochi, H. E. Chia, A. L. Ogonowsky, S. Chiang, N. Filipovic, A. G. Weiden, E. E. Hadley, S. E. Gabriel and A. M. Leconte . (2015). Taq DNA polymerase mutants and 2’ modified sugar recognition. Biochemistry 54: 5999.

  • A. M. Leconte, G. T. Hwang, S. Matsuda, P. Capek, Y. Hari, and F. E. Romesberg . (2008). Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet. J. Am. Chem. Soc. 130: 2336.

  • A. M. Leconte, B. C. Dickinson, D. D. Yang, I. A. Chen, B. Allen, D. R. Liu . (2013). A Population-Based Experimental Model for Protein Evolution: Effects of Mutation Rate and Selection Stringency on Evolutionary Outcomes. Biochemistry 52: 1490.